Hyderabad: The expert committee report of the Central Drugs Standards Control Organisation, a copy of which is with DC, revealed that the ill-effects of the fixed combination drugs (FDCs) were devastating.
Safety concerns for kids, drug-to-drug reactions, hepatotoxic (liver toxic), antibiotic resistance and emergence of drug resistance from the fixed combination drugs were the major findings of the expert committee.
Therapeutically inconsistent and pharmaco-dynamically irrelevant combinations were also named.
The Centre has recently banned 344 combination drugs based on the report by the committee constituted for examination of FDCs permitted for manufacture for sale without due approval by the Drug Controller General of India. The committee also evaluated data in connection with FDCs and found huge health aberrations....