105th Day Of Lockdown

Maharashtra2119871152629026 Tamil Nadu114978665711571 Delhi100823720883115 Gujarat36858263231967 Uttar Pradesh2863619109809 Telangana2573314781306 Karnataka2531710529402 West Bengal2298715235779 Andhra Pradesh211979745252 Rajasthan2092216320465 Haryana1777013393276 Madhya Pradesh1528411579617 Bihar12525901497 Assam12523788314 Odisha10097648654 Jammu and Kashmir86755318138 Punjab64914494132 Kerala5623334128 Chhatisgarh3305264414 Uttarakhand3230262143 Jharkhand2877206820 Goa190311568 Tripura169212191 Manipur14307710 Himachal Pradesh107876410 Puducherry104351714 Nagaland6443030 Chandigarh4924017 Arunachal Pradesh270922 Mizoram1971390 Sikkim125650 Meghalaya94432
Lifestyle Health and Wellbeing 26 Jul 2018 Researchers explain ...

Researchers explain how 'traffic jams' can also occur in your brain

ANI
Published Jul 26, 2018, 12:02 pm IST
Updated Jul 26, 2018, 12:02 pm IST
It can cause Parkinson's disease.
Researchers explain how 'traffic jams' can also occur in your brain. (Photo: Pixabay)
 Researchers explain how 'traffic jams' can also occur in your brain. (Photo: Pixabay)

Washington: Turns out, 'Traffic jams' can also occur in your brain and they can be damaging.

Researchers at Friedrich-Alexander-Universitat Erlangen-Nürnberg (FAU) have been able to confirm that they have been able to prove disrupted transportation routes in nerve cells are a significant cause of Parkinson's disease.

 

Nerve fibres give nerve cells their characteristic long shape. Measuring up to one metre in length, they form the contact points to other nerve cells.

In order to carry out the important task of communicating with other nerve cells, the fine branches of these nerve fibres and their ends, called synapses, must be regularly supplied with energy from the cell body.

If this energy supply is interrupted, the synapses are destroyed. Connections between nerve cells are then disrupted, which can lead to the cells dying off. This process is typical for the development of brain disorders such as Parkinson's disease.

Researchers have now succeeded in demonstrating that a type of 'traffic jam' in the nerve cells could be the cause.

They discovered that the traffic jam is triggered by a protein called alpha-synuclein, which is also found in healthy nerve cells. In abnormal nerve cells, the protein forms deposits, or even lumps, leading to a delay, disrupting the energy supply of the nerve fibres and, ultimately, damaging the synapses.

The researchers were also able to demonstrate this mechanism in cell cultures taken from patients with Parkinson's. A small skin sample was taken from affected patients. These skin cells were then converted into stem cells, which can be developed into any type of cell, and in this case, into nerve cells.

The full findings are present in the journal- Proceedings of the National Academy of Sciences.

...




ADVERTISEMENT
ADVERTISEMENT
ADVERTISEMENT
ADVERTISEMENT
ADVERTISEMENT