Lifestyle Health and Wellbeing 16 Sep 2017 Intense exercises ma ...

Intense exercises may slow growth of breast cancer tumours: Study

DECCAN CHRONICLE | DECCAN CHRONICLE
Published Sep 16, 2017, 5:13 pm IST
Updated Sep 16, 2017, 5:18 pm IST
A research based in Denmark shows that intense physical activity that causes breathlessness releases certain chemicals in the body (Photo: Pexels)
 A research based in Denmark shows that intense physical activity that causes breathlessness releases certain chemicals in the body (Photo: Pexels)

Exercise is known to have a lot of positive effects, however recent studies show that it can release compounds in the body that can slow down the growth of tumours in breast cancer patients. 

A research based in Denmark shows that intense physical activity that causes breathlessness releases certain chemicals in the body. 

These chemicals contain compounds called catecholamines and particularly epinephrine, which help suppress the growth of tumour cells.

In a statement to Reuters Health, senior study author, Pernille Hojman, from University of Copenhagen said, "It is important to highlight that exercise training and epinephrine did not completely prevent tumor formation, but induced a 50 percent reduction"

Adding that while exercise training can never replace anti-cancer therapy, it is still an effective supportive strategy, which in addition to the biological effects has been shown to increase the patients’ quality of life and sense of empowerment.

There are several studies that have shown how regular fitness can reduce a woman’s risk of breast cancer and, in those who already have breast cancer, may keep it from coming back. 

Hojman’s team used experimental mice implanted with human breast cancer tumors as well as tumor cells in test tubes to investigate how serum samples collected from healthy women and breast cancer patients before and after exercise affect the development of the breast tumor cells, and what mechanisms were involved.

They found that serum samples taken after exercise reduced the ability of tumor cells to grow in test tubes or in mice. 

The researchers traced anti-tumor activity to a rise in epinephrine and norepinephrine that occurs with moderately intense exercise and its effect on the a gene-signaling pathway known as 'Hippo' which helps to suppress tumor development.

"In our study, we found that breast cancer patients in adjuvant chemotherapy, were indeed capable of performing the required exercise, so it is feasible for cancer patients to do the exercise training we are proposing," said Hojman to the Daily Mail.

Hojman believes in the certainty of the results of this study to possibly work in other types of cancer as well.

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