Washington: The rate of elevated systolic blood pressure (SBP) has increased substantially globally between 1990 and 2015, putting more people at an increased heart disease and stroke risk including in India, a new study has warned.
In 2015 an estimated 3.5 billion adults had systolic blood pressure of at least 110 to 115 millimetre of mercury (mm Hg) and 874 million adults had SBP of 140 mm Hg or higher, according to researchers from the University of Washington in
the US. Systolic blood pressure of at least 110 mm Hg has been related to multiple cardiovascular and kidney outcomes, including ischemic heart disease, cerebrovascular disease and chronic kidney disease, said researchers.
The global obesity epidemic may further increase SBP in some populations. Quantifying the levels of SBP is important to guide prevention policies and interventions. Researchers estimated the association between SBP of at
least 110 to 115 mm Hg and SBP of 140 mm Hg or higher and the burden of different causes of death and disability by age and sex, based on 844 studies from 154 countries (published between 1980 and 2015) of 8.69 million participants.
They found that the rate of elevated SBP (110-115 or greater and 140 mm Hg or greater) increased substantially between 1990 and 2015, and disability-adjusted life-years (DALYs) and deaths associated with elevated SBP also increased.
DALY is a measure of overall disease burden, expressed as the number of years lost due to ill-health, disability or early death.
Researchers also found that systolic blood pressure of at least 110 to 115 mm Hg was associated with more than 10 million deaths and more than 212 million DALYs in 2015, a 1.4-fold increase since 1990. Compared with all other specific risks quantified in a 2015 study, SBP of at least 110 to 115 mm Hg was the leading global contributor to preventable death in 2015, they said.
"These estimates are concerning given that in 2015, an estimated 3.5 billion individuals had an SBP level of at least 110 to 115 mm Hg," researchers said.
The largest numbers of SBP-related deaths were caused by ischemic heart disease (4.9 million), hemorrhagic stroke (2 million) and ischemic stroke (1.5 million), they found. Five countries accounted for more than half of global
DALYs associated with SBP of at least 110 to 115 mm Hg: China, India, Russia, Indonesia, and the US.
"Both the projected number and prevalence rate of SBP of at least 110 to 115 mm Hg are likely to continue to increase globally. These findings support increased efforts to control the burden of SBP of at least 110 to 115 mm Hg to reduce disease burden," researchers added. The study appears in the journal JAMA.
