Women’s New Hormone Hero
Study suggests creatine supplementation may help improve irregular periods and support certain fertility markers in women
Creatine has long been the unofficial mascot of the weight room. Think: protein shakers, flexed biceps, and gym selfies. Not exactly something you’d expect to see in a conversation about menstrual cycles or fertility. And yet — here we are. A new study suggests that creatine supplementation may help improve irregular periods and support certain fertility markers in women. Naturally, this has sparked curiosity. Could a supplement best known for muscle gains quietly be useful for hormone health too?
Before we start tossing creatine into our morning smoothies in the name of ovulation, let’s break it down — simply, clearly, and without the gym jargon.
Creatine Explained
Creatine is a naturally occurring compound found in your muscles (and in small amounts in foods like red meat). Its main job? Helping your cells produce quick energy. Think of it as your body’s “instant battery pack.” When you lift weights, sprint, or do anything high-intensity, creatine helps your body regenerate energy faster. That’s why athletes love it. But here’s the twist: muscles aren’t the only tissues that need energy. Your brain needs it. Your metabolism needs it. And yes — your reproductive system needs it too.
Look At Period Cycles
Your menstrual cycle isn’t just about hormones floating around randomly. It’s a highly coordinated, energy-demanding process. Ovulation alone requires significant cellular work. Your ovaries rely heavily on mitochondria — the tiny “power plants” inside cells — to function properly.
Dr. Meera Sinha, Consultant Obstetrician and Gynaecologist, explains it this way. “Ovulation is an energy-intensive process. If cellular energy production isn’t optimal, it can influence hormone signalling and cycle regularity. Supporting mitochondrial health may, in theory, support reproductive function.”
In the recent study, women with irregular cycles were given creatine over a monitored period. Researchers observed improvements in menstrual regularity in some participants, along with better ovulatory markers and metabolic shifts. Important phrase: in some participants. This isn’t a miracle powder. But it’s enough to make scientists curious.
The PCOS Connection
One of the most interesting angles here is metabolism. Many women who struggle with irregular cycles — particularly those with PCOS (Polycystic Ovary Syndrome) — also experience insulin resistance. And insulin resistance can disrupt hormone balance. 8–13% of women of reproductive age globally have PCOS. Up to 70% of women with PCOS have insulin resistance. Resistance training can improve insulin sensitivity by 25–40% in women with metabolic dysfunction. Dr. Aditi Rao, Endocrinologist and Women’s Hormone Specialist, adds perspective. “There is a strong link between metabolic health and menstrual regularity. If a supplement supports cellular energy and improves metabolic function, it could indirectly support hormonal balance. However, we are not at a stage where creatine should be recommended as a fertility intervention.”
Not A Hormone Hack
Let’s be clear: creatine is not an infertility treatment. It is not a replacement for medical care. It does not “fix” hormones overnight. What it may do — based on early findings — is support the energy systems that help your body function efficiently. And that’s an important distinction.
Hormones don’t operate in isolation. They respond to stress, sleep, nutrition, body composition, and metabolic health. Supporting overall cellular energy may create a better environment for balance — but it’s one piece of a very large puzzle.
Interestingly, many women are already taking creatine — just for different reasons. Anjali Deshmukh, certified Gym trainer, says she’s seen a noticeable shift in how women approach supplements “Five years ago, women were hesitant about creatine because they thought it would make them bulky. Now, they understand it helps with strength, recovery, and performance. If it also has potential benefits for overall health, that’s a bonus — but performance is still the main reason most of my clients use it.”
She also addresses a common myth, “Creatine doesn’t make you gain fat. Some women notice slight water retention initially, but it’s temporary and usually inside the muscle, not under the skin.” In other words, you won’t wake up looking like a bodybuilder overnight.
This Conversation Matters
For decades, sports nutrition research focused primarily on men. Women were underrepresented in clinical trials. It’s encouraging to see more studies examining how supplements interact with female physiology. Women
are no longer separating “fitness health” from “hormone health.” Strength training, metabolic health, and reproductive wellness are increasingly understood as interconnected. Creatine entering this space doesn’t mean it’s a magic solution. But it does highlight something important: energy matters. Your cycle isn’t just a hormonal event. It’s a whole-body process.
The gym bro supplement may be getting a rebrand — but for now, it’s cautiously stepping into the women’s health conversation. And honestly? That’s progress.
Ladies, Pay Attention!
If you’re considering creatine, here’s the practical part:
• Typical dose: 3–5 grams daily
• No loading phase is necessary for general use
• Stay hydrated
• Mild water retention is normal in the beginning
• Avoid if you have kidney disease unless supervised by a doctor
• Talk to your healthcare provider if you’re trying to conceive or manage a hormonal condition.