Washington: A new study has shed light on Viagra. Viagra can have anti-cancer, antibacterial, and therapeutic effects if used with new drugs, says the study.
It has also shown how existing drugs such as Viagra or Cialis and a derivative of the drug Celebrex, for example, can reduce the activity of a specific chaperone protein, with the potential for anti-tumour and anti-Alzheimer's disease effects.
The authors describe how OSU-03012, an experimental compound derived from the drug celecoxib (Celebrex) interacts with Viagra or Cialis to reduce levels of chaperone proteins and reduced levels of HSPA5.
Dna K can interfere with virus replication, promote bacterial cell death, and even make drug-resistant "superbugs" susceptible to existing antibiotics.
In the article "HSPA5/Dna K May Be a Useful Target for Human Disease Therapies", Laurence Booth, Jane Roberts, and Paul Dent, Virginia Commonwealth University, Richmond, provided a comprehensive discussion of the HSPA5/Dna K chaperone protein and the published evidence for its role in various human diseases.
The authors describe how OSU-03012, an experimental compound derived from the drug celecoxib (Celebrex) interacts with Viagra or Cialis to reduce levels of chaperone proteins. Reduced levels of HSPA5 and Dna K can interfere with virus replication, promote bacterial cell death, and even make drug-resistant "superbugs" susceptible to existing antibiotics.
Carol Shoshkes Reiss, PhD, Editor-in-Chief, of DNA and Cell Biology and
The study is published in described in a Review article in DNA and Cell Biology, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.
