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Beneficial bacteria in nose can help resist pathogenic bacteria

This is an early stage in exploration of the molecular mechanisms that sculpt the composition of the nasal microbiome.

When two bacteria interact, they inhibit the virulence of Staphylococcus Aureus, claims a study.

According to the study conducted by senior author Dr. Katherine P. Lemon, first-author Dr. Matthew M. Ramsey and Dr. Marcelo Freire at the Forsyth Institute, besides Rebecca Gabrilska and Dr. Kendra Rumbaugh of the Texas Tech University, a further understanding of this interaction will help researchers to develop new treatments for preventing Staphylococcus Aureus infections.

They also believe that their research on interactions between benign members of the human microbiome and bacteria that exhibit similar dual characteristics, could lead to the development of novel treatments for other diseases.

"Our research helps set the stage for the development of small molecules and, potentially, probiotic therapies for promoting health by actively managing nasal microbiome composition," said Dr.Lemon. "This research identifies a role for

Corynebacterium species in suppressing Staphylococcus Aureus virulence, and is an exciting early stage in our exploration of the molecular mechanisms that sculpt the composition of the nasal microbiome and influence colonization by pathobionts," she said.

"We look forward to an increase in research on commensal-pathobiont interactions within the human microbiome and an ever- increasing understanding of the significance of our beneficial bacteria partners," she added.

The full paper, titled "Staphylococcus aureus shifts towards commensalism in response to Corynebacterium species" is available in the Frontiers in Microbiology website.

( Source : ANI )
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